• Users Online: 159
  • Print this page
  • Email this page
Year : 2020  |  Volume : 6  |  Issue : 4  |  Page : 441-447

Risk factors associated with recurrence within 90 days of ischemic stroke onset in chinese medicine hospital: A national cross-sectional study in China

1 Department of Evidence-Based Medicine Basic Research, Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China
2 Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China
3 Department of Neurology, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China
4 Department of Neurology, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, China
5 Department of Neurology, Dongzhimen Hospital Beijing University of Chinese Medicine, Beijing, China
6 Department of Research, Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing, China

Correspondence Address:
Prof. Yan-Ming Xie
Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/wjtcm.wjtcm_32_20

Rights and Permissions

Objective: The short- and long-term risk factors for stroke recurrence may be different. This study is aimed to determine the risk factors for recurrence within 90 days in patients with ischemic stroke in China. Method: This was cross-sectional registry-based study in Chinese medicine hospitals from eight provinces and ten cities in China between November 3, 2016 and May 28, 2018. Two thousand one hundred and twenty patients with ischemic stroke aged between 35 and 80 years. Stroke recurrence was defined as an outcome indicator. Computed tomography/magnetic resonance imaging was used as a diagnostic tool for stroke recurrence. Patients' age, sex, height, weight, body mass index (BMI), education level, medical history, family history, smoking, and drinking were recorded. Routine laboratory examinations were performed. Associated factors were investigated by calculating the odds ratio (OR) using logistic regression modeling. Results: In all, 2120 patients were included in the study, 712 (33.6%) of whom were women and 1408 (66.4%) were men, with a mean age of 62.84 ± 9.35 years. Eighty-two patients experienced stroke recurrence within 90 days, and the accumulative recurrence rates of stroke were 3.9% (95% confidence interval [CI], 3.0%–4.7%). The binary logistic analysis showed that previous history of one (OR = 8.113; 95% CI, 4.497–14.637), two (OR = 8.848; 95% CI, 4.025–9.449), or ≥3 ischemic strokes (OR = 24.599; 95% CI, 9.307–65.018), and BMI <18.5 kg/m2 (OR = 2.842; 95% CI, 1.000–8.075) were independently associated with stroke recurrence within 90 days. Conclusions: The accumulative recurrence rate of ischemic stroke was 3.9% within 90 days. Number of previous history of ischemic stroke and BMI <18.5 kg/m2 were independent risk factors for stroke recurrence. Medical history and solar terms of ischemic stroke were not found to be associated with stroke recurrence within 90 days. Effective secondary prevention for patients with a previous history of ischemic stroke is urgently needed to address this stroke recurrence burden.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded20    
    Comments [Add]    

Recommend this journal